{"id":8393,"date":"2022-04-05T11:39:43","date_gmt":"2022-04-05T03:39:43","guid":{"rendered":"https:\/\/www.phytogaia.com\/?p=8393"},"modified":"2022-04-05T12:46:50","modified_gmt":"2022-04-05T04:46:50","slug":"plain","status":"publish","type":"post","link":"https:\/\/www.phytogaia.com\/index.php\/zh\/2022\/04\/05\/plain\/","title":{"rendered":"\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"8393\" class=\"elementor elementor-8393\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3c27859 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3c27859\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-39f56ed\" data-id=\"39f56ed\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a21a054 elementor-widget elementor-widget-heading\" data-id=\"a21a054\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b4936dc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b4936dc\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-aaf69ad\" data-id=\"aaf69ad\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cae5e9f elementor-widget elementor-widget-image\" data-id=\"cae5e9f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"612\" height=\"408\" src=\"https:\/\/www.phytogaia.com\/wp-content\/uploads\/2022\/04\/istockphoto-942696360-612x612-1.jpg\" class=\"attachment-large size-large wp-image-8408\" alt=\"\" srcset=\"https:\/\/www.phytogaia.com\/wp-content\/uploads\/2022\/04\/istockphoto-942696360-612x612-1.jpg 612w, https:\/\/www.phytogaia.com\/wp-content\/uploads\/2022\/04\/istockphoto-942696360-612x612-1-300x200.jpg 300w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e06e14c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e06e14c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f5d7d0\" data-id=\"3f5d7d0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-063f238 elementor-widget elementor-widget-text-editor\" data-id=\"063f238\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>2022 <\/strong><strong>\u5e74<\/strong><strong> 3 <\/strong><strong>\u6708<\/strong><strong> 29 <\/strong><strong>\u65e5<\/strong><strong> &#8211; <\/strong><strong>\u7f8e\u56fd\u7ebd\u7ea6<\/strong> &#8211; \u68d5\u6988\u679c\u5b9e\u4e2d\u7684\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u901a\u8fc7\u6062\u590d\u6297\u6c27\u5316\u80fd\u529b\u548c\u6291\u5236\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u6765\u5bf9\u6297\u80ba\u7ea4\u7ef4\u5316 (Pulmonary Fibrosis, PF) \u7684\u91cd\u8981\u80ba\u90e8\u4fdd\u62a4\u5242\u3002 \u7ec4\u7ec7\u75c5\u7406\u5b66\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u6cbb\u7597\u53ef\u663e\u7740\u6539\u5584BLM\u5f15\u8d77\u7684\u80ba\u635f\u4f24\uff0c\u5982\u6700\u8fd1\u4e1c\u5357\u5927\u5b66\u548c\u4e2d\u56fd\u9a6c\u6765\u897f\u4e9a\u68d5\u6988\u6cb9\u59d4\u5458\u4f1a\u7814\u7a76\u6240\u7684\u7814\u7a76\u4eba\u5458\u5728 Nutrients \u4e0a\u53d1\u8868\u7684\u4e00\u9879\u7814\u7a76\u62a5\u544a\u3002 \u80ba\u7ea4\u7ef4\u5316(PF) \u662f\u4e00\u79cd\u4e3b\u8981\u7531\u7ec6\u83cc\u6216\u75c5\u6bd2\u611f\u67d3\u5f15\u8d77\u7684\u6162\u6027\u3001\u8fdb\u884c\u6027\u548c\u6700\u7ec8\u7ec8\u672b\u671f\u75be\u75c5\u3002\u6700\u8fd1\uff0c\u5728\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e(COVID-19\/<em>\u65b0\u51a0<\/em><em>)<\/em>\u540e\u60a3\u8005\u4e2d\u62a5\u5bfc\u4e86\u4e0d\u540c\u7a0b\u5ea6\u7684\u80ba\u7ea4\u7ef4\u5316(PF)\u3002<\/p><p>\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u5458\u5411\u80ba\u7ea4\u7ef4\u5316\u8bf1\u5bfc\u7684 Sprague-Dawley (SD) \u5927\u9f20\u8865\u5145\u751f\u7406\u76d0\u6c34\u3001\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u590d\u5408\u7269\uff08\u6bcf\u5929 50\u3001200mg\/kg \u4f53\u91cd\uff09\u3001\u68d5\u6988\u6df7\u5408\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u6216\u540c\u65f6\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\uff08200mg\/kg \u6bcf\u5929\u4f53\u91cd\uff09\u548c\u80e1\u841d\u535c\u7d20\uff08\u6bcf\u5929 10mg\/kg \u4f53\u91cd\uff09\uff0c\u6301\u7eed 28 \u5929\u3002 \u901a\u8fc7\u8c03\u8282 TGF-\u03b2\/Smad\u3001PI3K\/Akt\/mTOR \u548c NF-\u03baB \u4fe1\u53f7\u901a\u8def\uff0c\u7814\u7a76\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u5bf9\u535a\u6765\u9709\u7d20 (BLM) \u8bf1\u5bfc\u80ba\u7ea4\u7ef4\u5316\u7684\u6cbb\u7597\u6548\u679c\u3002<\/p><p>\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u68d5\u6988\u80e1\u841d\u535c\u7d20\u6cbb\u7597\u5747\u88ab\u53d1\u73b0\u53ef\u663e\u7740\u6062\u590d BLM \u8bf1\u5bfc\u7684\u6297\u708e\u548c\u6297\u6c27\u5316\u529f\u80fd\u7684\u6539\u53d8\u3002 \u8fd9\u4e9b\u6cbb\u7597\u4f3c\u4e4e\u901a\u8fc7\u4e0a\u8c03\u6297\u6c27\u5316\u72b6\u6001\u3001\u4e0b\u8c03 MMP-7 \u548c\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u8868\u8fbe\uff08IL-1\u03b2\u3001IL-6\u3001MPO\u3001TGF-\u03b21 \u548c TNF-\u03b1\uff09\u3001\u6c27\u5316\u5e94\u6fc0\uff08MDA \uff09\u548c\u7ec6\u80de\u5916\u57fa\u8d28\uff08HYP \u548c MMP-7\uff09\u548c\u51cf\u5c11\u80f6\u539f\u86cb\u767d\u7684\u79ef\u7d2f\u3002<\/p><p>\u7ec4\u7ec7\u75c5\u7406\u5b66\u7684\u53d1\u73b0\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0c\u8865\u5145\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u53ef\u663e\u7740\u51cf\u8f7b BLM \u8bf1\u5bfc\u7684\u5927\u9f20\u80ba\u635f\u4f24\u6216\u80ba\u7ea4\u7ef4\u5316\u3002\u8fd9\u662f\u6709\u53f2\u4ee5\u6765\u7b2c\u4e00\u4efd\u7814\u7a76\u8bc1\u660e\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u5927\u9f20 BLM \u8bf1\u5bfc\u7684 \u80ba\u7ea4\u7ef4\u5316PF \u5177\u6709\u9884\u9632\u4f5c\u7528\u7684\u62a5\u544a\u3002\u7814\u7a76\u4eba\u5458\u5f97\u51fa\u7ed3\u8bba\uff0c\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u53ef\u80fd\u662f\u4e00\u79cd\u51cf\u8f7b\u6216\u51cf\u5f31 \u80ba\u7ea4\u7ef4\u5316PF \u7684\u65b0\u578b\u6cbb\u7597\u6027\u5316\u5408\u7269\u3002<\/p><p><em>\u201c<\/em><em>\u6211\u4eec\u5bf9\u8fd9\u4e9b\u65b0\u53d1\u73b0\u611f\u5230\u9f13\u821e\uff0c\u56e0\u4e3a\u8fd9\u662f\u7b2c\u4e00\u4e2a\u7814\u7a76\u663e\u793a\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5728\u6062\u590d\u80ba\u90e8\u6297\u6c27\u5316\u80fd\u529b\u548c\u6291\u5236\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u4ee5\u53ca\u6539\u5584\u80ba\u635f\u4f24\u65b9\u9762\u7684\u6f5c\u529b\u3002<\/em><em>\u00a0<\/em><em>\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0c\u68d5\u6988\u690d\u7269\u8425\u517b\u7d20\u5177\u6709\u534f\u540c\u4f5c\u7528\uff0c\u53ef\u80fd\u7528\u4f5c\u540e\u65b0\u51a0\u75ca\u6108\u60a3\u8005\u6216\u80ba\u90e8\u5065\u5eb7\u7684\u81b3\u98df\u8865\u5145\u5242\uff0c\u5f53\u7136\u8fd9\u9700\u8981\u4e34\u5e8a\u7814\u7a76\u8fdb\u884c\u8bc1\u5b9e\u3002<\/em><em>\u201d<\/em>\u9996\u5e2d\u7814\u7a76\u5458\u5b59\u535a\u58eb\u8bf4<em>\u3002<\/em><\/p><p>\u201c<em>\u76ee\u524d\u6709\u5927\u91cf\u62a5\u544a\u663e\u793a\uff0c\u4e25\u91cd\u7684\u65b0\u51a0\u611f\u67d3\u4f1a\u589e\u52a0\u80ba\u7ea4\u7ef4\u5316\u7684\u98ce\u9669\uff0c\u8fd9\u5728\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u538b\u6216\u5fc3\u8840\u7ba1\u75be\u75c5\u7b49\u5408\u5e76\u75c7\u60a3\u8005\u4e2d\u66f4\u4e3a\u5e38\u89c1\u3002\u80ba\u7ea4\u7ef4\u5316<\/em><em>(PF)<\/em><em>\u4ecd\u7136\u65e0\u6cd5\u6cbb\u6108\u3002 \u56e0\u6b64\uff0c\u8fd9\u9879\u65b0\u7814\u7a76\u5728\u65b0\u51a0\u540e\u65f6\u4ee3\u662f\u4e00\u4e2a\u53d7\u6b22\u8fce\u7684\u6d88\u606f\uff0c\u56e0\u4e3a\u6211\u4eec\u8fdb\u5165\u4e86\u5e94\u5bf9\u5b83\u7684\u9636\u6bb5\uff0c<\/em>\u201d<strong>\u98de\u9014\u76d6\u4e9a\uff08<\/strong><strong>PhytoGaia<\/strong><strong>\uff09<\/strong>\u79d1\u5b66\u4e8b\u52a1\u4e13\u5bb6 Ariati Aris \u533b\u751f\u8865\u5145\u3002<\/p><p>\u201c<em>\u8fd9\u4e00\u53d1\u73b0\u589e\u52a0\u4e86\u8d8a\u6765\u8d8a\u591a\u7684\u79d1\u5b66\u8bc1\u636e\uff0c\u68d5\u6988\u679c\u5b9e\u4e2d\u63d0\u53d6\u7684\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u53d1\u6325\u5f3a\u5927\u7684\u6297\u6c27\u5316\u548c\u6297\u708e\u7279\u6027\u65b9\u9762\u5177\u6709\u534f\u540c\u4f5c\u7528\u3002 \u98de\u9014\u76d6\u4e9a\u7684<\/em><em> TocoGaia<sup>TM<\/sup><\/em><em>\uff08\u751f\u80b2\u4e09\u70ef\u915a\uff09\u548c<\/em><em> CaroGaia<sup>TM<\/sup><\/em><em>\uff08\u80e1\u841d\u535c\u7d20\uff09\u6709\u591a\u79cd\u5f62\u5f0f\u53ef\u4f9b\u9009\u62e9\uff0c\u4ee5\u6ee1\u8db3\u4e0d\u540c\u7684\u5e94\u7528\uff0c\u5982\u8f6f\u80f6\u56ca\u3001\u7247\u5242\u3001\u4e24\u7247\u660e\u80f6\u80f6\u56ca\u3001\u529f\u80fd\u6027\u98df\u54c1\u548c\u996e\u6599\u3002 \u6211\u4eec\u671f\u5f85\u4e0e\u54c1\u724c\u516c\u53f8\u5408\u4f5c\uff0c\u7814\u53d1\u51fa\u79d1\u5b66\u9a71\u52a8\u7684\u4ea7\u54c1\u6216\u590d\u5408\u7ef4\u751f\u7d20\uff0c\u4ee5\u589e\u5f3a\u6297\u6c27\u5316\u3001\u62a4\u80ba\u548c\u514d\u75ab\u529f\u80fd<\/em>\uff0c\u201d<strong>\u98de\u9014\u76d6\u4e9a\uff08<\/strong><strong>PhytoGaia<\/strong><strong>\uff09<\/strong> \u526f\u603b\u88c1 \u8c22\u5bb6\u826f\uff08Bryan\uff09\u5148\u751f\u8bf4\u3002<\/p><p><strong><u>\u53c2\u8003\u6587\u732e<\/u><\/strong><strong><u>:<\/u><\/strong><\/p><ol><li>Lu, Y. <em>et al<\/em>. (2022). Potential \u201cTherapeutic\u201d Effects of Tocotrienol-Rich Fraction (TOCOTRIENOL) and Carotene \u201cAgainst\u201d Bleomycin-Induced Pulmonary Fibrosis in Rats via TGF-\/Smad, PI3K\/Akt\/mTOR and NF- B Signaling Pathways. <em>Nutrients<\/em>, 14, 1094.<\/li><li>George, P.M. et al. (2022). Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy. The <em>Lancet Respiratory Medicine<\/em>, 8:807-15.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528 2022 \u5e74 3 \u6708 29 \u65e5 &#8211; \u7f8e\u56fd\u7ebd\u7ea6 &#8211; \u68d5\u6988\u679c\u5b9e\u4e2d\u7684\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u901a\u8fc7\u6062\u590d\u6297\u6c27\u5316\u80fd\u529b\u548c\u6291\u5236\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u6765\u5bf9\u6297\u80ba\u7ea4\u7ef4\u5316 (Pulmonary Fibrosis, PF) \u7684\u91cd\u8981\u80ba\u90e8\u4fdd\u62a4\u5242\u3002 \u7ec4\u7ec7\u75c5\u7406\u5b66\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u6cbb\u7597\u53ef\u663e\u7740\u6539\u5584BLM\u5f15\u8d77\u7684\u80ba\u635f\u4f24\uff0c\u5982\u6700\u8fd1\u4e1c\u5357\u5927\u5b66\u548c\u4e2d\u56fd\u9a6c\u6765\u897f\u4e9a\u68d5\u6988\u6cb9\u59d4\u5458\u4f1a\u7814\u7a76\u6240\u7684\u7814\u7a76\u4eba\u5458\u5728 Nutrients \u4e0a\u53d1\u8868\u7684\u4e00\u9879\u7814\u7a76\u62a5\u544a\u3002 \u80ba\u7ea4\u7ef4\u5316(PF) \u662f\u4e00\u79cd\u4e3b\u8981\u7531\u7ec6\u83cc\u6216\u75c5\u6bd2\u611f\u67d3\u5f15\u8d77\u7684\u6162\u6027\u3001\u8fdb\u884c\u6027\u548c\u6700\u7ec8\u7ec8\u672b\u671f\u75be\u75c5\u3002\u6700\u8fd1\uff0c\u5728\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e(COVID-19\/\u65b0\u51a0)\u540e\u60a3\u8005\u4e2d\u62a5\u5bfc\u4e86\u4e0d\u540c\u7a0b\u5ea6\u7684\u80ba\u7ea4\u7ef4\u5316(PF)\u3002 \u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u5458\u5411\u80ba\u7ea4\u7ef4\u5316\u8bf1\u5bfc\u7684 Sprague-Dawley (SD) \u5927\u9f20\u8865\u5145\u751f\u7406\u76d0\u6c34\u3001\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u590d\u5408\u7269\uff08\u6bcf\u5929 50\u3001200mg\/kg \u4f53\u91cd\uff09\u3001\u68d5\u6988\u6df7\u5408\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u6216\u540c\u65f6\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\uff08200mg\/kg \u6bcf\u5929\u4f53\u91cd\uff09\u548c\u80e1\u841d\u535c\u7d20\uff08\u6bcf\u5929 10mg\/kg \u4f53\u91cd\uff09\uff0c\u6301\u7eed 28 \u5929\u3002 \u901a\u8fc7\u8c03\u8282 TGF-\u03b2\/Smad\u3001PI3K\/Akt\/mTOR \u548c NF-\u03baB \u4fe1\u53f7\u901a\u8def\uff0c\u7814\u7a76\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u5bf9\u535a\u6765\u9709\u7d20 (BLM) \u8bf1\u5bfc\u80ba\u7ea4\u7ef4\u5316\u7684\u6cbb\u7597\u6548\u679c\u3002 \u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u68d5\u6988\u80e1\u841d\u535c\u7d20\u6cbb\u7597\u5747\u88ab\u53d1\u73b0\u53ef\u663e\u7740\u6062\u590d BLM \u8bf1\u5bfc\u7684\u6297\u708e\u548c\u6297\u6c27\u5316\u529f\u80fd\u7684\u6539\u53d8\u3002 \u8fd9\u4e9b\u6cbb\u7597\u4f3c\u4e4e\u901a\u8fc7\u4e0a\u8c03\u6297\u6c27\u5316\u72b6\u6001\u3001\u4e0b\u8c03 MMP-7 \u548c\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u8868\u8fbe\uff08IL-1\u03b2\u3001IL-6\u3001MPO\u3001TGF-\u03b21 \u548c TNF-\u03b1\uff09\u3001\u6c27\u5316\u5e94\u6fc0\uff08MDA \uff09\u548c\u7ec6\u80de\u5916\u57fa\u8d28\uff08HYP \u548c MMP-7\uff09\u548c\u51cf\u5c11\u80f6\u539f\u86cb\u767d\u7684\u79ef\u7d2f\u3002 \u7ec4\u7ec7\u75c5\u7406\u5b66\u7684\u53d1\u73b0\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0c\u8865\u5145\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u53ef\u663e\u7740\u51cf\u8f7b BLM \u8bf1\u5bfc\u7684\u5927\u9f20\u80ba\u635f\u4f24\u6216\u80ba\u7ea4\u7ef4\u5316\u3002\u8fd9\u662f\u6709\u53f2\u4ee5\u6765\u7b2c\u4e00\u4efd\u7814\u7a76\u8bc1\u660e\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u5927\u9f20 BLM \u8bf1\u5bfc\u7684 \u80ba\u7ea4\u7ef4\u5316PF [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76,90],"tags":[],"class_list":["post-8393","post","type-post","status-publish","format-standard","hentry","category-76","category-news-press-releases-ch"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528 - PhytoGaia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.phytogaia.com\/index.php\/zh\/2022\/04\/05\/plain\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528 - PhytoGaia\" \/>\n<meta property=\"og:description\" content=\"\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u5bf9\u80ba\u7ea4\u7ef4\u5316\u7684\u80ba\u90e8\u4fdd\u62a4\u4f5c\u7528 2022 \u5e74 3 \u6708 29 \u65e5 &#8211; \u7f8e\u56fd\u7ebd\u7ea6 &#8211; \u68d5\u6988\u679c\u5b9e\u4e2d\u7684\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u901a\u8fc7\u6062\u590d\u6297\u6c27\u5316\u80fd\u529b\u548c\u6291\u5236\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u6765\u5bf9\u6297\u80ba\u7ea4\u7ef4\u5316 (Pulmonary Fibrosis, PF) \u7684\u91cd\u8981\u80ba\u90e8\u4fdd\u62a4\u5242\u3002 \u7ec4\u7ec7\u75c5\u7406\u5b66\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u590d\u5408\u7269\u6cbb\u7597\u53ef\u663e\u7740\u6539\u5584BLM\u5f15\u8d77\u7684\u80ba\u635f\u4f24\uff0c\u5982\u6700\u8fd1\u4e1c\u5357\u5927\u5b66\u548c\u4e2d\u56fd\u9a6c\u6765\u897f\u4e9a\u68d5\u6988\u6cb9\u59d4\u5458\u4f1a\u7814\u7a76\u6240\u7684\u7814\u7a76\u4eba\u5458\u5728 Nutrients \u4e0a\u53d1\u8868\u7684\u4e00\u9879\u7814\u7a76\u62a5\u544a\u3002 \u80ba\u7ea4\u7ef4\u5316(PF) 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TGF-\u03b2\/Smad\u3001PI3K\/Akt\/mTOR \u548c NF-\u03baB \u4fe1\u53f7\u901a\u8def\uff0c\u7814\u7a76\u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u80e1\u841d\u535c\u7d20\u5bf9\u535a\u6765\u9709\u7d20 (BLM) \u8bf1\u5bfc\u80ba\u7ea4\u7ef4\u5316\u7684\u6cbb\u7597\u6548\u679c\u3002 \u68d5\u6988\u751f\u80b2\u4e09\u70ef\u915a\u548c\u68d5\u6988\u80e1\u841d\u535c\u7d20\u6cbb\u7597\u5747\u88ab\u53d1\u73b0\u53ef\u663e\u7740\u6062\u590d BLM \u8bf1\u5bfc\u7684\u6297\u708e\u548c\u6297\u6c27\u5316\u529f\u80fd\u7684\u6539\u53d8\u3002 \u8fd9\u4e9b\u6cbb\u7597\u4f3c\u4e4e\u901a\u8fc7\u4e0a\u8c03\u6297\u6c27\u5316\u72b6\u6001\u3001\u4e0b\u8c03 MMP-7 \u548c\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u8868\u8fbe\uff08IL-1\u03b2\u3001IL-6\u3001MPO\u3001TGF-\u03b21 \u548c TNF-\u03b1\uff09\u3001\u6c27\u5316\u5e94\u6fc0\uff08MDA \uff09\u548c\u7ec6\u80de\u5916\u57fa\u8d28\uff08HYP \u548c MMP-7\uff09\u548c\u51cf\u5c11\u80f6\u539f\u86cb\u767d\u7684\u79ef\u7d2f\u3002 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